Polynucleotides are injectable skin treatments designed to support skin repair, hydration, texture and overall skin quality.
About treatment
Polynucleotides are advanced injectable skin treatments designed to support skin repair, hydration and overall tissue quality. Rather than working like traditional dermal fillers, polynucleotides focus on improving the condition of the skin itself — helping it appear smoother, fresher, more resilient and better supported over time.
At Cellia MD, polynucleotide treatment is approached with precision, care and a medically led understanding of skin health. The aim is not to alter facial shape or add visible volume, but to support regenerative skin improvement in a subtle, natural-looking way. This makes the treatment especially relevant for clients who want healthier-looking skin without an obvious “treated” appearance.
This treatment is commonly explored by clients searching for polynucleotides, polynucleotide treatment, injectable skin repair or advanced skin repair treatment. It may be suitable where the skin appears tired, dull, dehydrated, crepey, less elastic or affected by fine texture changes.
Polynucleotides may also be considered for delicate areas where skin quality is the main concern and where heavier correction would not be appropriate. For many clients, the value lies in gradual refinement — skin that looks calmer, fresher and more polished over time, while still looking entirely natural.
- Skin quality improvement – Polynucleotides are designed to support smoother, fresher and more refined-looking skin by improving the visible condition of the skin itself.
- Hydration and freshness – Treatment may help improve skin hydration and support a more comfortable, healthy-looking appearance.
- Fine lines and texture – Polynucleotides may be suitable where fine lines, uneven texture, dullness or crepey skin are affecting overall skin quality.
- Delicate-area support – In suitable cases, polynucleotides may be considered for delicate areas where subtle skin repair and refinement are preferred over volume.
- Regenerative skin repair – This treatment is often chosen by clients looking for gradual improvement through a regenerative, medically guided approach.
- Overall skin resilience – Polynucleotides may help support skin that appears less elastic, less firm or less refreshed than before.
Procedure Length
30 minutes
Downtime
Minimal; small bumps, redness, tenderness or mild swelling may appear at the injection points and usually settle within a few days. Bruising can occur and may last longer.
Results
Results develop gradually. Skin may begin to appear fresher and better hydrated within a few weeks, with texture, elasticity and overall skin quality improving over a course of treatment.
Longevity
Results vary depending on skin condition, lifestyle and treatment plan. A course of treatments is usually recommended for best results, with maintenance discussed during consultation.
Aftercare
Keep the skin clean and avoid touching, rubbing or massaging the treated area. Avoid makeup for around 12 hours and avoid heavy exercise, alcohol, heat, saunas, steam rooms, swimming pools and active skincare for 24–48 hours.
FAQ
No. Polynucleotides are not used like traditional dermal fillers. They are focused on skin quality and repair rather than volume, contour or facial reshaping.
Polynucleotides may help with tired-looking skin, dehydration, fine lines, dullness, uneven texture, reduced elasticity and delicate skin quality concerns.
Polynucleotides may be considered for delicate areas, including under-eye skin quality concerns, but suitability must be assessed carefully during consultation.
This depends on your skin condition, treatment area and goals. Many clients benefit from a course of treatments, followed by maintenance where appropriate.
Results are gradual. Some clients notice improved hydration and freshness within a few weeks, while more visible skin quality changes usually develop over time.
Downtime is usually minimal, although redness, swelling, small bumps or bruising can occur at the injection points and may take a few days to settle.
Yes, polynucleotide treatment is available at Cellia MD, with treatment planning based on your skin quality, suitability and individual goals.
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